What is the difference between GHRP-2 and PEG-MGF?

GHRP-2: Synthetic hexapeptide that stimulates pulsatile growth hormone release from the anterior pituitary by acting on the ghrelin receptor (GHSR-1a). PEG-MGF: Pegylated form of MGF; activates muscle stem cells (satellite cells) to repair and regenerate muscle tissue after damage

Is GHRP-2 FDA approved?

GHRP-2 is not FDA approved and restricted from compounding. It is discussed for research and educational purposes only, not as medical guidance.

How is GHRP-2 administered in research settings?

In research settings, GHRP-2 is typically administered via the subcutaneous or intramuscular routes. PeptideBase does not provide dosing or administration instructions.

How is PEG-MGF administered in research settings?

In research settings, PEG-MGF is typically administered via the subcutaneous or intramuscular routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›GHRP-2 vs PEG-MGF

Peptide Comparison

GHRP-2 vs PEG-MGF

Name: GHRP-2 vs PEG-MGF — Per-mg Price Comparison
Creator: PeptideBase
License: https://peptidebase.io/terms

Both are GH / IGF Axis peptides.

GHRP-2

Growth Hormone Releasing Peptide 2

PerformanceBanned from CompoundingResearch Only

Half-life: 15–60 minutes

42 providers listed

Full GHRP-2 profile →

PEG-MGF

Pegylated Mechano Growth Factor

RecoveryResearch Only

Half-life: Several days (vs. minutes for native MGF)

10 providers listed

Full PEG-MGF profile →

Bottom line

GHRP-2 has published research citations on file; PEG-MGF does not yet — the main evidence gap between them.

Quick Verdict

GHRP-2

Evidence

Observational

Half-life

15–60 minutes

PEG-MGF

Evidence

Not rated

Half-life

Several days (vs. minutes for native MGF)

Which One Should You Choose?

Your goal	Better option
Has published research citations	GHRP-2
Lower typical price per mg	GHRP-2
More provider options (42 vs 10)	GHRP-2

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

GHRP-2

PEG-MGF

Mechanism Family

GH / IGF Axis

Half-life

15–60 minutes

Several days (vs. minutes for native MGF)

FDA Status

banned from compounding

nomination withdrawn

Admin Routes

subcutaneous, intramuscular

Availability

Research Only

Providers

42 listed

10 listed

FDA Update

Sep 2023

—

Avail. Notes

Approved for diagnostic GH stimulation testing in Japan (Kaken Pharma) but NOT FDA-approved. Listed on the FDA Category 2 'significant safety risks' bulk-substances list (503B designation, added September 2023). WADA prohibited. Research chemical in US.

PEGylated IGF-1 splice variant with extended half-life. No FDA approval. WADA prohibited. Not on any FDA list. Sold as research chemical. No NDA or IND.

Research Evidence

GHRP-2

ObservationalCohort study · 2 key studies · most recent 2020

PEG-MGF

No citations on file

Research Citations

GHRP-2

Cohort2020 · Endocrine Journal

Preoperative growth hormone (GH) peak values during a GH releasing peptide-2 test reflect the severity of hyp…

Review2014 · Neurologia Medico-Chirurgica

Adult growth hormone deficiency: current concepts

PEG-MGF

No citations on file.

About GHRP-2

Synthetic hexapeptide that stimulates pulsatile growth hormone release from the anterior pituitary by acting on the ghrelin receptor (GHSR-1a). Commonly stacked with GHRH analogs such as CJC-1295 or Sermorelin to amplify GH output synergistically.

Research Areas

potent GH release via GHS-R1a agonismco-stimulation of cortisol and prolactin (non-selective profile)synergistic GH amplification when combined with GHRH analogsvalidated diagnostic GH stimulation agent (Japan clinical use)

About PEG-MGF

Pegylated form of MGF; activates muscle stem cells (satellite cells) to repair and regenerate muscle tissue after damage

Research Areas

muscle repairsatellite cell activationpost-injury recovery

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

GHRP-2

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Suggested Monitoring

IGF-1Fasting glucoseHbA1cCortisolInsulin

GHRP-2 stimulates GH and cortisol release. Research protocols measure IGF-1 for GH axis response and baseline cortisol given the compound's adrenal stimulation. Glucose markers are standard given GH's effect on insulin sensitivity.

PEG-MGF

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Used Together?

GHRP-2

Corticosteroids
Research notes that GHRP-2 stimulates cortisol and ACTH release via the HPA axis. Combined use with corticosteroid medications may affect glucocorticoid regulation. Consult your prescriber before combining.

Price (per mg)

GHRP-2

$5.90/mg

$3.90 – $8.00 range

27 vendors

View price index →Find providers →

PEG-MGF

$21.50/mg

$17.28 – $23.59 range

5 vendors

View price index →Find providers →

Find Providers

Where to source these peptides

Providers offering

GHRP-2

42 listed

Browse directory →

Providers offering

PEG-MGF

10 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More GH / IGF Axis Comparisons

Browse all peptides →

Educational research tools — not medical advice.

Cite this page

Data last updated July 22, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). GHRP-2 vs PEG-MGF — Per-mg Price Comparison. Retrieved July 22, 2026, from https://peptidebase.io/peptides/compare/ghrp-2/peg-mgf

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