Home›Research›Compare›GHRP-6 vs IGF-2
Peptide ComparisonGHRP-6 vs IGF-2
Both are GH / IGF Axis peptides.
GHRP-6
Growth Hormone Releasing Peptide-6
Half-life: 15-60 minutes
39 providers listed
IGF-2
Insulin-like Growth Factor 2
Half-life: ~10-20 minutes
No providers listed yet
IGF-2 carries stronger published evidence (Case series, 6 key studies) than GHRP-6 (Review, 1); both are research compounds.
GHRP-6
Half-life
15-60 minutes
IGF-2
Half-life
~10-20 minutes
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | IGF-2 |
| Less frequent dosing (longer half-life) | GHRP-6 |
| More provider options (39 vs 0) | GHRP-6 |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
GHRP-6
IGF-2
IGF-2
IGF-2-mediated hypoglycemia in a patient with a phyllodes tumor of the breast: a rare presentation of non-isl…
Proteomics and ex vivo plaque culture identify the insulin-like growth factor axis as a potential regulator o…
TGF-β inhibits muscle differentiation by blocking autocrine signaling pathways initiated by IGF-II
Autocrine growth factor signaling by insulin-like growth factor-II mediates MyoD-stimulated myocyte maturation
+2 more
About GHRP-6
Ghrelin receptor agonist; stimulates pituitary GH release and increases appetite via hypothalamic ghrelin pathways
About IGF-2
Binds IGF-1R and insulin receptor variant A; promotes anabolic signaling in muscle and fat; activates PI3K/Akt/mTOR pathway; different receptor binding profile than IGF-1
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
GHRP-6
Under clinical review
Being verified by our medical team before we display contraindications for this peptide.
GHRP-6 produces stronger cortisol and prolactin stimulation than selective GH peptides. Research protocols measure IGF-1 for GH axis response and baseline cortisol. Glucose markers are standard given GH's effect on insulin sensitivity.
IGF-2
Under clinical review
Being verified by our medical team before we display contraindications for this peptide.
GHRP-6
Corticosteroids
Research notes that GHRP-6 stimulates cortisol and ACTH release via the HPA axis. Combined use with corticosteroid medications may affect glucocorticoid regulation. Consult your prescriber before combining.
GHRP-6
IGF-2
Not enough vendor pricing yet.
Where to source these peptides
PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
More GH / IGF Axis Comparisons
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Cite this page
Data last updated August 26, 2026
Free to reference and republish with attribution to PeptideBase. Choose a format:
PeptideBase. (2026). GHRP-6 vs IGF-2 — Per-mg Price Comparison. Retrieved September 11, 2026, from https://peptidebase.io/peptides/compare/ghrp-6/igf-2