What is the difference between Epithalon and Livagen?

Epithalon: Epithalon is believed to activate telomerase, the enzyme responsible for maintaining telomere length, with several in vitro and animal studies reporting telomere elongation. Livagen: Tetrapeptide bioregulator for hepatocytes; activates gene expression in liver cells; promotes liver cell regeneration; restores lymphocyte activity via liver-mediated immune pathways

Is Epithalon FDA approved?

Epithalon is the subject of a favorable FDA advisory committee vote but not FDA approved, and its legal status for compounding is unchanged. It is discussed for research and educational purposes only, not as medical guidance.

Is Livagen FDA approved?

Livagen is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is Epithalon administered in research settings?

In research settings, Epithalon is typically administered via the subcutaneous or intravenous routes. PeptideBase does not provide dosing or administration instructions.

How is Livagen administered in research settings?

In research settings, Livagen is typically administered via the subcutaneous or intramuscular routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›Epithalon vs Livagen

Peptide Comparison

Epithalon vs Livagen

Name: Epithalon vs Livagen — Per-mg Price Comparison
Creator: PeptideBase
License: https://peptidebase.io/terms

Both are Longevity & Cellular peptides.

Epithalon

Epitalon

LongevityAdvisory Vote: FavorableResearch Only

Half-life: 30–60 minutes

176 providers listed

Full Epithalon profile →

Livagen

Lys-Glu-Asp-Glu

LongevityNot EvaluatedResearch Only

Half-life: Unknown

3 providers listed

Full Livagen profile →

Bottom line

Livagen has published research citations on file; Epithalon does not yet — the main evidence gap between them.

Quick Verdict

Epithalon

Half-life

30–60 minutes

Livagen

Half-life

Unknown

Which One Should You Choose?

Your goal	Better option
Has published research citations	Livagen
More provider options (176 vs 3)	Epithalon

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

Epithalon

Livagen

Mechanism Family

Longevity & Cellular

Half-life

30–60 minutes

Unknown

FDA Status

advisory committee recommended

not evaluated

Admin Routes

subcutaneous, intravenous

subcutaneous, intramuscular

Availability

Research Only

Providers

176 listed

3 listed

FDA Update

Jul 2026

—

Avail. Notes

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) from Khavinson Institute, Russia. Telomerase activator in research. No FDA approval, no NDA or IND. Not on any FDA list. Research chemical.

Russian liver peptide bioregulator (Lys-Glu-Asp-Gly) from Khavinson Institute. Studied for aging and hepatic function. No FDA approval, no NDA or IND. Research chemical in US.

Research Evidence

Epithalon

No citations on file

Livagen

Review · 2 key studies · most recent 2022

Research Citations

Epithalon

No citations on file.

Livagen

Review2022 · International Journal of Molecular Sciences

Bioavailability and Biological Activities of Food-Derived Di- and Tripeptides: In Silico and In Vitro Studies

Review2020 · Stem Cell Reviews and Reports

Short Peptides in the Treatment of Age-Related Diseases

About Epithalon

Epithalon is believed to activate telomerase, the enzyme responsible for maintaining telomere length, with several in vitro and animal studies reporting telomere elongation. It also appears to regulate the expression of p53 and other cell-cycle control genes, modulate the hypothalamic-pituitary axis via pineal gland activity, and upregulate antioxidant defences including superoxide dismutase and catalase.

Research Areas

telomerase activation and telomere elongation in cell researchmelatonin pathway regulation via pineal gland bioregulator mechanismantioxidant and anti-aging effects (Khavinson-class tetrapeptide)subcutaneous dosing — 10–20 injection courses studied in longevity research

About Livagen

Tetrapeptide bioregulator for hepatocytes; activates gene expression in liver cells; promotes liver cell regeneration; restores lymphocyte activity via liver-mediated immune pathways

Research Areas

liver cell regenerationhepatoprotectionimmune restoration via liverchromatin activation

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

Epithalon

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Livagen

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Used Together?

Epithalon

GHK-Cu
Research suggests Epithalon and GHK-Cu may produce complementary longevity-associated effects when combined. Epithalon is studied for telomere maintenance and pineal function, while GHK-Cu is studied for antioxidant gene expression and tissue remodeling — different mechanisms in aging research.

Price (per mg)

Epithalon

$3.50/mg

$2.55 – $4.18 range

51 vendors

View price index →Find providers →

Livagen

$3.00/mg

$2.75 – $3.15 range

9 vendors

View price index →Find providers →

Find Providers

Where to source these peptides

Providers offering

Epithalon

176 listed

Browse directory →

Providers offering

Livagen

3 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More Longevity & Cellular Comparisons

Browse all peptides →

Educational research tools — not medical advice.

Cite this page

Data last updated August 26, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). Epithalon vs Livagen — Per-mg Price Comparison. Retrieved September 12, 2026, from https://peptidebase.io/peptides/compare/epithalon/livagen

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