Home›Research›Compare›Epithalon vs Humanin
Peptide ComparisonEpithalon vs Humanin
Both are Longevity & Cellular peptides.
Epithalon
Epitalon
Half-life: 30–60 minutes
173 providers listed
Humanin
HN
Half-life: ~2-4 hours
9 providers listed
Humanin has a longer half-life than Epithalon, so it generally needs less frequent dosing.
Epithalon
Evidence
Half-life
30–60 minutes
Humanin
Evidence
Half-life
~2-4 hours
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | Humanin |
| Less frequent dosing (longer half-life) | Humanin |
| More provider options (173 vs 9) | Epithalon |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
Epithalon
Humanin
Epithalon
Humanin
Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and Mitochondrial Dysfunction.
Humanin Mitigates Aβ-Induced Retinal Pigment Epithelium Injury via AMPK-Beclin1-Dependent Mitophagy.
Humanin Restores Metabolic Hormone Homeostasis of Leptin, Ghrelin, Irisin and Asprosin in Streptozotocin-Indu…
Mitochondrial-derived Peptides and Cytoprotection in ARDS: Emerging Therapeutic Promise of Humanin.
+7 more
About Epithalon
Epithalon is believed to activate telomerase, the enzyme responsible for maintaining telomere length, with several in vitro and animal studies reporting telomere elongation. It also appears to regulate the expression of p53 and other cell-cycle control genes, modulate the hypothalamic-pituitary axis via pineal gland activity, and upregulate antioxidant defences including superoxide dismutase and catalase.
About Humanin
Mitochondria-derived peptide; binds gp130 receptor, activates STAT3/JAK pathway; inhibits BAX-mediated apoptosis; improves insulin sensitivity
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
Epithalon
No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.
Humanin
No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.
Epithalon
GHK-Cu
Research suggests Epithalon and GHK-Cu may produce complementary longevity-associated effects when combined. Epithalon is studied for telomere maintenance and pineal function, while GHK-Cu is studied for antioxidant gene expression and tissue remodeling — different mechanisms in aging research.
Epithalon
Humanin
Not enough vendor pricing yet.
Where to source these peptides
Epithalon
173 listed
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Providers offeringHumanin
9 listed
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PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
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Cite this page
Data last updated July 22, 2026
Free to reference and republish with attribution to PeptideBase. Choose a format:
PeptideBase. (2026). Epithalon vs Humanin — Per-mg Price Comparison. Retrieved July 22, 2026, from https://peptidebase.io/peptides/compare/epithalon/humanin